V23M (p.Val23Met) variant of CD28 (P10747)
V23M (p.Val23Met) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
V23M (p.Val23Met) variant details
- p.Val23Met
- rs1188026727
- gnomAD 2-203706581-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- CADD 14.50
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- Literature evidence available