V16I (p.Val16Ile) variant of CD28 (P10747)
V16I (p.Val16Ile) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
V16I (p.Val16Ile) variant details
- p.Val16Ile
- 1000Genomes rs150242792
- ESP rs150242792
- ExAC rs150242792
- TOPMed rs150242792
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.38
- MetaLR 0.39
- MetaSVM -0.65
- CADD 18.10
- PolyPhen-2 0.05
- SIFT 0.14
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.05)
- Structural context available