T17K (p.Thr17Lys) variant of CD28 (P10747)
T17K (p.Thr17Lys) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
T17K (p.Thr17Lys) variant details
- p.Thr17Lys
- 1000Genomes rs568613966
- ExAC rs568613966
- gnomAD rs568613966
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.49
- MetaLR 0.42
- MetaSVM -0.56
- CADD 22.20
- PolyPhen-2 0.11
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available