T17I (p.Thr17Ile) variant of CD28 (P10747)
T17I (p.Thr17Ile) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T17I (p.Thr17Ile) variant details
- p.Thr17Ile
- 1000Genomes rs568613966
- ExAC rs568613966
- gnomAD rs568613966
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.42
- MetaLR 0.45
- MetaSVM -0.54
- CADD 23.90
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the 1KG:ACB population (allele frequency 0.0054)
- Structural context available