S61N (p.Ser61Asn) variant of CD28 (P10747)
S61N (p.Ser61Asn) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S61N (p.Ser61Asn) variant details
- p.Ser61Asn
- ExAC rs35290181
- TOPMed rs35290181
- gnomAD rs35290181
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.20
- MetaLR 0.18
- MetaSVM -0.84
- CADD 24.00
- PolyPhen-2 0.84
- SIFT 0.07
- Most common in the Amish population (allele frequency 0.025)
- Structural context available