S61G (p.Ser61Gly) variant of CD28 (P10747)
S61G (p.Ser61Gly) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S61G (p.Ser61Gly) variant details
- p.Ser61Gly
- gnomAD 2-203726761-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.10
- CADD 20.70
- PolyPhen-2 0.11
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available