S43C (p.Ser43Cys) variant of CD28 (P10747)
S43C (p.Ser43Cys) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
S43C (p.Ser43Cys) variant details
- p.Ser43Cys
- gnomAD 2-203726708-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.97
- CADD 23.20
- PolyPhen-2 0.72
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available