Q74R (p.Gln74Arg) variant of CD28 (P10747)
Q74R (p.Gln74Arg) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
Q74R (p.Gln74Arg) variant details
- p.Gln74Arg
- gnomAD 2-203726801-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -1.07
- CADD 8.50
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available