P12P (p.Pro12Pro) variant of CD28 (P10747)
P12P (p.Pro12Pro) in CD28 (P10747) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
P12P (p.Pro12Pro) variant details
- p.Pro12Pro
- rs1559548001
- gnomAD 2-203706529-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.283
- CADD 15.90
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available
- Literature evidence available