P12L (p.Pro12Leu) variant of CD28 (P10747)
P12L (p.Pro12Leu) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P12L (p.Pro12Leu) variant details
- p.Pro12Leu
- ExAC rs202094371
- TOPMed rs202094371
- gnomAD rs202094371
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- CADD 4.50
- SIFT 0.38
- Most common in the Latino/Admixed American population (allele frequency 0.0001)
- Structural context available