P12A (p.Pro12Ala) variant of CD28 (P10747)
P12A (p.Pro12Ala) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
P12A (p.Pro12Ala) variant details
- p.Pro12Ala
- rs1693159763
- gnomAD 2-203706527-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- CADD 15.20
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available
- Literature evidence available