N45D (p.Asn45Asp) variant of CD28 (P10747)
N45D (p.Asn45Asp) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
N45D (p.Asn45Asp) variant details
- p.Asn45Asp
- Ensembl rs201776549
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.19
- MetaLR 0.34
- MetaSVM -0.62
- CADD 23.00
- PolyPhen-2 0.52
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available