N34S (p.Asn34Ser) variant of CD28 (P10747)
N34S (p.Asn34Ser) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
N34S (p.Asn34Ser) variant details
- p.Asn34Ser
- gnomAD 2-203726681-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.20
- MetaLR 0.35
- MetaSVM -0.62
- CADD 12.90
- PolyPhen-2 0.32
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available