M28V (p.Met28Val) variant of CD28 (P10747)
M28V (p.Met28Val) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
M28V (p.Met28Val) variant details
- p.Met28Val
- ExAC rs771698017
- TOPMed rs771698017
- gnomAD rs771698017
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.04
- MetaLR 0.24
- MetaSVM -0.98
- CADD 6.19
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available