M28I (p.Met28Ile) variant of CD28 (P10747)
M28I (p.Met28Ile) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
M28I (p.Met28Ile) variant details
- p.Met28Ile
- Ensembl rs1005123826
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.07
- MetaLR 0.40
- MetaSVM -0.52
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available