L59V (p.Leu59Val) variant of CD28 (P10747)
L59V (p.Leu59Val) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L59V (p.Leu59Val) variant details
- p.Leu59Val
- gnomAD 2-203726755-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.15
- MetaLR 0.10
- MetaSVM -0.99
- CADD 10.50
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available