L55F (p.Leu55Phe) variant of CD28 (P10747)
L55F (p.Leu55Phe) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L55F (p.Leu55Phe) variant details
- p.Leu55Phe
- gnomAD 2-203726743-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.38
- MetaLR 0.47
- MetaSVM 0.03
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available