L38F (p.Leu38Phe) variant of CD28 (P10747)
L38F (p.Leu38Phe) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L38F (p.Leu38Phe) variant details
- p.Leu38Phe
- gnomAD 2-203726692-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.39
- MetaLR 0.49
- MetaSVM -0.24
- CADD 22.60
- PolyPhen-2 0.86
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available