L2L (p.Leu2Leu) variant of CD28 (P10747)
L2L (p.Leu2Leu) in CD28 (P10747) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
L2L (p.Leu2Leu) variant details
- p.Leu2Leu
- rs142565527
- gnomAD 2-203706702-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.657
- CADD 9.61
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available