L22W (p.Leu22Trp) variant of CD28 (P10747)
L22W (p.Leu22Trp) in CD28 (P10747) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
L22W (p.Leu22Trp) variant details
- p.Leu22Trp
- gnomAD 2-203726641-AT-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.652
- CADD 28.60
- Population evidence available
- Structural context available
- Literature evidence available