L22L (p.Leu22Leu) variant of CD28 (P10747)
L22L (p.Leu22Leu) in CD28 (P10747) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- rs748989473
- gnomAD 2-203726644-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.312
- CADD 9.45
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available
- Literature evidence available