K41T (p.Lys41Thr) variant of CD28 (P10747)
K41T (p.Lys41Thr) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
K41T (p.Lys41Thr) variant details
- p.Lys41Thr
- gnomAD 2-203726702-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.12
- MetaLR 0.23
- MetaSVM -0.79
- CADD 22.80
- PolyPhen-2 0.47
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available