K41R (p.Lys41Arg) variant of CD28 (P10747)
K41R (p.Lys41Arg) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
K41R (p.Lys41Arg) variant details
- p.Lys41Arg
- gnomAD 2-203726702-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.04
- MetaLR 0.19
- MetaSVM -0.91
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available