G58R (p.Gly58Arg) variant of CD28 (P10747)
G58R (p.Gly58Arg) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
G58R (p.Gly58Arg) variant details
- p.Gly58Arg
- gnomAD 2-203726752-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.40
- MetaLR 0.30
- MetaSVM -0.41
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available