G18E (p.Gly18Glu) variant of CD28 (P10747)
G18E (p.Gly18Glu) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G18E (p.Gly18Glu) variant details
- p.Gly18Glu
- ExAC rs747456956
- gnomAD rs747456956
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.12
- MetaLR 0.12
- MetaSVM -1.07
- CADD 9.51
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available