F51L (p.Phe51Leu) variant of CD28 (P10747)
F51L (p.Phe51Leu) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
F51L (p.Phe51Leu) variant details
- p.Phe51Leu
- gnomAD 2-203726731-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.38
- MetaLR 0.53
- MetaSVM -0.07
- CADD 23.40
- PolyPhen-2 0.71
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available