F47V (p.Phe47Val) variant of CD28 (P10747)
F47V (p.Phe47Val) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
F47V (p.Phe47Val) variant details
- p.Phe47Val
- gnomAD 2-203726719-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.25
- MetaLR 0.30
- MetaSVM -0.88
- CADD 17.80
- PolyPhen-2 0.10
- SIFT 0.58
- Population evidence available
- Structural context available
- Literature evidence available