F11L (p.Phe11Leu) variant of CD28 (P10747)
F11L (p.Phe11Leu) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
F11L (p.Phe11Leu) variant details
- p.Phe11Leu
- gnomAD 2-203706727-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.34
- MetaLR 0.41
- MetaSVM -0.85
- CADD 15.10
- PolyPhen-2 0.01
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available