D60G (p.Asp60Gly) variant of CD28 (P10747)
D60G (p.Asp60Gly) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D60G (p.Asp60Gly) variant details
- p.Asp60Gly
- TOPMed rs1347784700
- gnomAD rs1347784700
- Missense
- Variant Prioritization Score for Impact Estimate 0.53
- REVEL 0.50
- MetaLR 0.64
- MetaSVM 0.31
- CADD 25.00
- PolyPhen-2 0.65
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available