D33Y (p.Asp33Tyr) variant of CD28 (P10747)
D33Y (p.Asp33Tyr) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
D33Y (p.Asp33Tyr) variant details
- p.Asp33Tyr
- gnomAD 2-203726677-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.24
- MetaLR 0.45
- MetaSVM -0.44
- CADD 12.40
- PolyPhen-2 0.86
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available