A62V (p.Ala62Val) variant of CD28 (P10747)
A62V (p.Ala62Val) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A62V (p.Ala62Val) variant details
- p.Ala62Val
- ExAC rs771716313
- gnomAD rs771716313
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -1.04
- CADD 22.20
- PolyPhen-2 0.71
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available