A62T (p.Ala62Thr) variant of CD28 (P10747)
A62T (p.Ala62Thr) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A62T (p.Ala62Thr) variant details
- p.Ala62Thr
- 1000Genomes rs187859903
- ExAC rs187859903
- TOPMed rs187859903
- gnomAD rs187859903
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.09
- MetaLR 0.10
- MetaSVM -1.04
- CADD 16.10
- PolyPhen-2 0.33
- SIFT 0.04
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available