A35E (p.Ala35Glu) variant of CD28 (P10747)
A35E (p.Ala35Glu) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A35E (p.Ala35Glu) variant details
- p.Ala35Glu
- cosmic curated COSV99048
- TOPMed rs1202305808
- gnomAD rs1202305808
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.03
- MetaLR 0.11
- MetaSVM -0.88
- CADD 0.10
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available