A35A (p.Ala35Ala) variant of CD28 (P10747)
A35A (p.Ala35Ala) in CD28 (P10747) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
A35A (p.Ala35Ala) variant details
- p.Ala35Ala
- rs41272649
- gnomAD 2-203726685-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0854
- CADD 0.67
- Most common in the 1KG:GBR population (allele frequency 0.029)
- Structural context available
- Cited in: Association study between polymorphisms of CD28, CTLA4 and ICOS and non-segmental vitiligo in a Korean population. (PMID 22977635)