A31V (p.Ala31Val) variant of CD28 (P10747)
A31V (p.Ala31Val) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A31V (p.Ala31Val) variant details
- p.Ala31Val
- ExAC rs760627956
- TOPMed rs760627956
- gnomAD rs760627956
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.03
- MetaLR 0.16
- MetaSVM -0.97
- CADD 0.50
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available