A31T (p.Ala31Thr) variant of CD28 (P10747)
A31T (p.Ala31Thr) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A31T (p.Ala31Thr) variant details
- p.Ala31Thr
- gnomAD rs1386535030
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.05
- MetaLR 0.32
- MetaSVM -0.84
- CADD 12.90
- PolyPhen-2 0.06
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available