A31G (p.Ala31Gly) variant of CD28 (P10747)
A31G (p.Ala31Gly) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
A31G (p.Ala31Gly) variant details
- p.Ala31Gly
- gnomAD 2-203726672-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.16
- MetaLR 0.45
- MetaSVM -0.54
- CADD 16.00
- PolyPhen-2 0.52
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available