Y28H (p.Tyr28His) variant of CD274 (Programmed cell death 1 ligand 1)
Y28H (p.Tyr28His) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
Y28H (p.Tyr28His) variant details
- p.Tyr28His
- Ensembl rs2131211084
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.08
- AlphaMissense 0.23
- MetaLR 0.02
- MetaSVM -1.15
- CADD 23.50
- PolyPhen-2 0.61
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available