Y12* (p.Tyr12Ter) variant of CD274 (Programmed cell death 1 ligand 1)

Y12* (p.Tyr12Ter) in CD274 (Programmed cell death 1 ligand 1) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.

Y12* (p.Tyr12Ter) variant details