W13R (p.Trp13Arg) variant of CD274 (Programmed cell death 1 ligand 1)
W13R (p.Trp13Arg) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
W13R (p.Trp13Arg) variant details
- p.Trp13Arg
- ExAC rs765955659
- gnomAD rs765955659
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.09
- AlphaMissense 0.20
- MetaLR 0.09
- MetaSVM -1.04
- CADD 19.20
- PolyPhen-2 0.21
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available