W13G (p.Trp13Gly) variant of CD274 (Programmed cell death 1 ligand 1)
W13G (p.Trp13Gly) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
W13G (p.Trp13Gly) variant details
- p.Trp13Gly
- gnomAD 9-5456150-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.07
- AlphaMissense 0.07
- MetaLR 0.09
- MetaSVM -1.00
- CADD 20.10
- PolyPhen-2 0.39
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available