W13C (p.Trp13Cys) variant of CD274 (Programmed cell death 1 ligand 1)
W13C (p.Trp13Cys) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
W13C (p.Trp13Cys) variant details
- p.Trp13Cys
- ExAC rs776345482
- TOPMed rs776345482
- gnomAD rs776345482
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.10
- AlphaMissense 0.10
- MetaLR 0.03
- MetaSVM -1.03
- CADD 15.20
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available