V30I (p.Val30Ile) variant of CD274 (Programmed cell death 1 ligand 1)
V30I (p.Val30Ile) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
V30I (p.Val30Ile) variant details
- p.Val30Ile
- gnomAD rs1819318390
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.14
- AlphaMissense 0.11
- MetaLR 0.29
- MetaSVM -0.80
- CADD 21.20
- PolyPhen-2 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available