V30A (p.Val30Ala) variant of CD274 (Programmed cell death 1 ligand 1)
V30A (p.Val30Ala) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V30A (p.Val30Ala) variant details
- p.Val30Ala
- TOPMed rs1344190674
- gnomAD rs1344190674
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.14
- AlphaMissense 0.13
- MetaLR 0.11
- MetaSVM -0.98
- CADD 19.80
- PolyPhen-2 0.13
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available