V29E (p.Val29Glu) variant of CD274 (Programmed cell death 1 ligand 1)
V29E (p.Val29Glu) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V29E (p.Val29Glu) variant details
- p.Val29Glu
- Ensembl rs2131211119
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.09
- AlphaMissense 0.13
- MetaLR 0.18
- MetaSVM -0.85
- CADD 17.50
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available