V23I (p.Val23Ile) variant of CD274 (Programmed cell death 1 ligand 1)
V23I (p.Val23Ile) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V23I (p.Val23Ile) variant details
- p.Val23Ile
- gnomAD rs1485681345
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.13
- AlphaMissense 0.12
- MetaLR 0.22
- MetaSVM -0.80
- CADD 20.70
- PolyPhen-2 0.32
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available