T37K (p.Thr37Lys) variant of CD274 (Programmed cell death 1 ligand 1)
T37K (p.Thr37Lys) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
T37K (p.Thr37Lys) variant details
- p.Thr37Lys
- gnomAD rs1314957482
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.26
- AlphaMissense 0.29
- MetaLR 0.06
- MetaSVM -1.18
- CADD 24.90
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available