T37I (p.Thr37Ile) variant of CD274 (Programmed cell death 1 ligand 1)
T37I (p.Thr37Ile) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T37I (p.Thr37Ile) variant details
- p.Thr37Ile
- gnomAD rs1314957482
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.23
- AlphaMissense 0.32
- MetaLR 0.03
- MetaSVM -1.10
- CADD 24.70
- PolyPhen-2 0.99
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available