T22T (p.Thr22Thr) variant of CD274 (Programmed cell death 1 ligand 1)
T22T (p.Thr22Thr) in CD274 (Programmed cell death 1 ligand 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
T22T (p.Thr22Thr) variant details
- p.Thr22Thr
- rs146564807
- gnomAD 9-5457092-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.118
- CADD 5.25
- Most common in the HGDP:MBUTI population (allele frequency 0.042)
- Structural context available
- Literature evidence available