S34T (p.Ser34Thr) variant of CD274 (Programmed cell death 1 ligand 1)
S34T (p.Ser34Thr) in CD274 (Programmed cell death 1 ligand 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S34T (p.Ser34Thr) variant details
- p.Ser34Thr
- ESP rs140304675
- ExAC rs140304675
- TOPMed rs140304675
- gnomAD rs140304675
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.10
- AlphaMissense 0.14
- MetaLR 0.02
- MetaSVM -0.92
- CADD 23.20
- PolyPhen-2 0.77
- Most common in the REMAINING population (allele frequency 0.00012)
- Structural context available